Starch-based bionanocomposite films infused with amoxicillin-loaded CuO nanoparticles and their enhanced antimicrobial activity against AMR pathogens
Rattachement africain : in, uz. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
The widespread use of plastic-based medical materials, such as bandages, syringes, and biomedical packaging, has led to serious health problems owing to their inappropriate disposal and non-biodegradability. This study focused on the fabrication and characterization of potato-starch-based films infused with amoxicillin-loaded CuONPs (AMX-CuONPs) for biomedical applications. CuONPs were synthesized using Bacopa monnieri leaf extract, which was functionalized with amoxicillin. The properties of the bio-nanocomposite films were characterized morphologically (SEM and EDX), mechanically (tensile strength and elongation at break), structurally (XRD and FTIR), and for biodegradability and antimicrobial activity. The AMX-CuONPs bio-nanocomposite film (AC-BF) exhibited a thickness of 0.69 mm, density of 1.33 g/cm 3 , tensile strength of 0.63 MPa, and the highest elongation break of 49%. XRD analysis revealed the amorphous nature of the film, while FTIR analysis revealed the functional groups such as C-H, O-H, C = O, C = C, and Cu-O, indicating AMX-CuONPs integration into the starch-based films. SEM analysis showed homogeneity and particles embedded on the surface of AC-BF. Furthermore, AC-BF showed rapid biodegradation within 35 days, whereas the maximum zone of inhibition was observed in Antimicrobial Resistance (AMR) and non-AMR bacterial strains. These results suggest the potential of these materials for biomedical packaging, wound healing bandages, and patch applications.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Starch-based bionanocomposite films infused with amoxicillin-loaded CuO nanoparticles and their enhanced antimicrobial activity against AMR pathogens
- Date Crossref
- 09/07/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Hemchandracharya North Gujarat University Department of Lifesciences pays non établi dans la noticeUniversité ou école supérieure
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Government of Gujarat pays non établi dans la noticeOrganisme public
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Gujarat Biotechnology Research Centre pays non établi dans la noticeOrganisme public
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Parul University Department of Pharmaceutics pays non établi dans la noticeUniversité ou école supérieure
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Andijan State University Department of Biology pays non établi dans la noticeUniversité ou école supérieure
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Bhakta Kavi Narsinh Mehta University Department of Life Sciences pays non établi dans la noticeUniversité ou école supérieure
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Gujarat State Biotechnology Mission (GSBTM) pays non établi dans la noticeInstitution
Department of Lifesciences — Hemchandracharya North Gujarat University, Government of Gujarat et Gujarat Biotechnology Research Centre, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.