A Comparative Clinical Study of Sugammadex and Neostigmine in Reversal of Vecuronium-Induced Neuromuscular Blockade in Adults

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Background: Sugammadex is a selective relaxant-binding agent that rapidly and effectively reverses neuromuscular blockade (NMB) induced by vecuronium. It reduced incidence of residual neuromuscular blockade (RNMB) is associated with improved patient safety, fewer postoperative respiratory complications. Objectives: To evaluate the effect of Sugammadex and Neostigmine for the reversal of Vecuronium induced neuro muscular blockades and its characteristics of recovery and the incidence of any adverse events. And to assess the hemodynamic parameters. Methods: This prospective comparative clinical study was conducted on 100 patients scheduled for elective surgery at Katihar Medical College, Katihar. Participants were randomly selected and allocated in two equal groups. The sample size was determined to be 50 patients in each group. During the preoperative assessment, the details of the study were explained to all participants. Written informed consent was obtained from patients who agreed to participate in the study.

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