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Accès ouvert déclaré 2026 preprint

Screening for and Treatment of Depression in Perinatal Women Living with HIV in Sub-Saharan Africa: A Scoping Review

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This study is a scoping review that aims to map the extent, range, and nature of evidence on depression screening and treatment among perinatal women living with HIV in sub-Saharan Africa. The review follows the Joanna Briggs Institute (JBI) framework and is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The review was undertaken because, despite growing evidence on perinatal depression among women living with HIV, existing reviews have been predominantly quantitative and narrowly focused on either prevalence estimation or specific treatment modalities. No prior scoping review has systematically mapped both screening and treatment evidence while incorporating qualitative, mixed-methods, and quantitative studies across the full perinatal period and the full geographic breadth of sub-Saharan Africa. The review specifically aims to: Describe the characteristics and geographic distribution of included studies. Identify the screening instruments used, their cultural adaptations, and the reported prevalence of depression. Characterise treatment modalities, delivery models, and outcomes. Identify factors associated with depression, screening uptake, and treatment response. Identify gaps in the existing literature to inform future research and policy.

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