Replication data for : Loa loa microfilaremia and dementia: a community-based cross-sectional study in southern Cameroon.

Résumé fourni par la source

The data originate from the present DELOCAM study, conducted in Cameroon among an adult population, as an extension of a research programme dedicated to the neurological morbidity of loiasis. They were assembled to jointly characterise, within the same individual, cognitive and functional status, exposure to chronic parasitic infections, and the associated cardiovascular, renal, and sociodemographic markers. This data collection addresses the near-complete absence of individual-level data linking parasitic exposure and cognitive ageing in a region where these infections are nonetheless highly prevalent. The acquisition aimed to estimate the frequency of cognitive impairment and dementia, and then to examine their association with filarial exposure — in particular Loa loa microfilaraemia — with other helminthiases, with markers of arterial stiffness and subclinical atherosclerosis (PWV, IMT), and with cardiometabolic risk factors. It further aimed to produce an individual-level dataset — structured, standardised, and reusable — combining, within the same population, quantitative parasitological phenotyping, domain-specific cognitive assessment, and cardiovascular characterisation. The value of this dataset lies in the rarity of the combination it documents within a single Central African population: microfilarial densities and helminthic positivity, domain-specific cognitive scores, and composite indices. It supports secondary analyses, integration into regional meta-analyses, and methodological work on the adaptation of cognitive and functional-autonomy instruments to this setting. Brief Abstract of the associated publication: Checkouri et al. report that higher Loa loa microfilarial blood density is associated with greater odds of cognitive impairment and dementia in a community-based cross-sectional study in southern Cameroon, identifying chronic filarial infection as a candidate, previously overlooked contributor to cognitive decline in rural Central Africa.