Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer

Le résumé fourni par la source

The Editors have retracted this article at the Authors’ request. After publication, concerns were raised regarding the tumour burden in some mice in the control arms of the experiments presented in Fig. 4b (NPPO1-NE, NPPO-4, NPPO-6, and MSKPCa10 grafts) and Fig. 5j (WCM1262 grafts). The authors have shared the underlying tumour measurement and mouse bodyweight data, which confirmed that animal welfare protocols were breached. An investigation by the Institutional Animal Care and Use Committee at Columbia University Irving Medical Center found that these experiments were not compliant with protocol endpoints. The authors regret this failure to adhere to the highest standards of animal experimentation. No other experimental data or analyses have been affected by the issues underlying the investigation or retraction.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.