Germinal center responses at barrier organ sites

Le résumé fourni par la source

In this review, we detail the features of barrier germinal centers (GC) that form in tertiary lymphoid structures (TLSs) within non-immune organs that host a local microbiome, and posit a framework of immunity where TLS-GCs created at barrier sites are a key part of normal humoral immunity, and that they form the first layer of an intended multi-layered and increasingly defensive adaptive immune system, providing complementary tissue-specific responses, alongside the local secondary lymphoid organ network and systemic immune responses.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.