The hidden burden of overlap syndrome: Sleep quality and functional impairment in chronic obstructive pulmonary disease

Résumé fourni par la source

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is associated with reduced functional capacity and a high prevalence of sleep-related disturbances. However, the relationship between sleep-related disturbances and functional capacity remains incompletely understood. OBJECTIVE: To investigate the associations between COPD severity, sleep quality, nocturnal respiratory disturbances, and functional capacity assessed by the 6-min walk test (6MWT). METHODS: Eighty clinically stable patients with COPD underwent spirometry, home sleep monitoring, Pittsburgh Sleep Quality Index (PSQI), and 6MWT. Correlation and multiple linear regression analyses were performed. RESULTS: <90% remained independently associated with walking distance. CONCLUSION: Increasing COPD severity was associated with poorer sleep quality, greater nocturnal oxygen desaturation, and lower functional capacity. Sleep-related variables were independently associated with 6MWT performance, suggesting that sleep assessment may provide complementary information in the evaluation of patients with COPD.

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