Advances in stress echocardiography: myocardial work for myocardial ischemia detection
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Le résumé fourni par la source
AIMS: This study explores the usefulness of myocardial work (MW) analysis for coronary artery disease (CAD) detection in patients undergoing dipyridamole stress echocardiography (Dip-SE). METHODS: We included 50 patients subjected to Dip-SE followed by coronary computed tomography angiography (CCTA) and/or invasive coronary angiography (ICA). Patients were subdivided into two groups, according to the results of CCTA/ICA: group 1 with CAD and group 2 without CAD. Subsequently, global longitudinal strain (GLS) and MW parameters were evaluated retrospectively at base, low and high dose in the entire population. RESULTS: GLS showed a nonsignificant increase from baseline to low dose and significantly decreased from low to high dose ( P = 0.015) in group 1. In contrast, GLS in group 2 increased throughout the test, with the largest increase from baseline to low dose ( P < 0.001). Global constructive work (GCW) and global wasted work (GWW) showed opposite behaviors in both groups: GCW decreased in group 1 ( P = 0.009) and remained substantially unchanged in group 2; conversely, GWW increased from low to high dose in group 1 ( P = 0.003), whereas it decreased in group 2 ( P = 0.047). The latter result was confirmed by global work efficiency (GWE), which decreased from low to high dose in group 1 ( P = 0.025) and increased in group 2 ( P = 0.001). Receiver-operating characteristics analysis revealed that GWE is the best parameter for identifying CAD (area under the curve = 0.845). A decrease in GWE of 1.5% (from low to high dose) provided better sensitivity (73%) and specificity (84%). CONCLUSIONS: GWE analysis may be useful in improving CAD detection during Dip-SE.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Advances in stress echocardiography: myocardial work for myocardial ischemia detection
- Date Crossref
- 22/06/2026
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Azienda Ospedaliera Universitaria Policlinico "G. Martino" pays non établi dans la noticeÉtablissement de santé
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Fatebenefratelli Hospital Cardiology Division pays non établi dans la noticeÉtablissement de santé
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University School of Milwaukee pays non établi dans la noticeUniversité ou école supérieure
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University of Wisconsin–Milwaukee pays non établi dans la noticeUniversité ou école supérieure
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University of Messina Department of Clinical and Experimental Medicine pays non établi dans la noticeUniversité ou école supérieure
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Wake Forest University School of Medicine Division of Cardiovascular Medicine-Milwaukee Clinical Campus pays non établi dans la noticeUniversité ou école supérieure
Azienda Ospedaliera Universitaria Policlinico "G. Martino", Cardiology Division — Fatebenefratelli Hospital et University School of Milwaukee, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.