Additional file 2 of Centrosomal protein 72 deficiency exacerbates liver fibrosis induced by Schistosoma japonicum infection

Résumé fourni par la source

Additional file 2. Figure S2. Pro-fibrotic and pro-inflammatory genes were up-regulated in Cep72−/− mice in CCl4-induced liver fibrosis according to RNA-seq. (A) Volcano plots illustrate the up- or downregulated genes in WT and Cep72−/− mice treated with CCl4, based on RNA-seq data. (B) Pathway analysis of RNA-seq data showing the differentially expressed upregulated genes and downregulated genes in WT and Cep72−/− CCl4 injected mice. (C) Heatmaps of fibrosis-related genes and inflammatory factors are shown according to RNA-seq of WT and Cep72−/− CCl4 injected mice.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.