Point-of-care testing in community pharmacies to improve antimicrobial stewardship in respiratory infections: a scoping review of effectiveness, implementation and cost-effectiveness
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Le résumé fourni par la source
Abstract Objective To explore evidence on effectiveness, feasibility, cost-effectiveness and implementation factors of point-of-care testing (PoCT) in community pharmacies for antimicrobial stewardship in respiratory tract infections (RTIs). Methodology A systematic scoping review of PoCT studies published between 1 January 2012 and 30 July 2025 included randomized and non-randomized trials, health economic evaluations, post-implementation surveys and qualitative studies. Study quality was assessed using critical appraisal tools. Quantitative outcomes were summarized descriptively, and implementation factors were mapped using the Consolidated Framework for Implementation Research. Results Twenty-seven of 2689 studies were included; all but one were from high-income countries. Non-comparative studies suggested that PoCT reduced antibiotic supply. In C-reactive protein (CRP)-PoCT studies (n = 3; 503 patients), a median of 79.5% (IQR 72.2%–85.4%) had CRP <20 mg/L, indicating no need for antibiotics, while 1.2% (IQR 0%–11.3%) had CRP >100 mg/L, suggesting antibiotics were required; 12% were referred to general practitioners. In Group A Streptococcus (GAS)-PoCT studies (n = 12; 53 918 patients), 24.9% (IQR 17.8%–28.5%) tested positive and 21.3% (IQR 16.8%–27%) received antibiotics. In influenza-PoCT studies (n = 5; 374 patients), 34% (IQR 19.8%–36.1%) tested positive and 25.5% (IQR 10.1%–31.8%) received antivirals. Limited health economic evidence suggested that GAS-PoCT may be cost saving or cost minimizing. Thirteen interventions were identified to improve PoCT adoption. Conclusion PoCT is feasible in community pharmacies to improve antimicrobial stewardship in RTIs. Successful uptake requires context-specific strategies, such as pharmacist training, collaboration with general practitioners and the implementation of appropriate reimbursement models. High-quality randomized trials are needed to confirm effectiveness and cost-effectiveness of pharmacy-led PoCT for policy implementation.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Point-of-care testing in community pharmacies to improve antimicrobial stewardship in respiratory infections: a scoping review of effectiveness, implementation and cost-effectiveness
- Date Crossref
- 30/04/2026
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Deakin University Institute for Health Transformation pays non établi dans la noticeUniversité ou école supérieure
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The University of Melbourne National Centre for Antimicrobial Stewardship pays non établi dans la noticeUniversité ou école supérieure
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Australia and New Zealand Banking Group pays non établi dans la noticeInstitution
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Monash Health pays non établi dans la noticeÉtablissement de santé
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Monash University pays non établi dans la noticeUniversité ou école supérieure
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Burnet Institute AMR-One Health Working Group pays non établi dans la noticeOrganisation à but non lucratif
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Curtin University EnAble Institute pays non établi dans la noticeUniversité ou école supérieure
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School of Medicine Institute for Mental and Physical Health and Clinical Translation (IMPACT) pays non établi dans la noticeUniversité ou école supérieure
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Great Southern Bank pays non établi dans la noticeInstitution
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Faculty of Medicine Monash Nursing and Midwifery pays non établi dans la noticeUniversité ou école supérieure
Institute for Health Transformation — Deakin University, National Centre for Antimicrobial Stewardship — The University of Melbourne et Australia and New Zealand Banking Group, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.