Self-Powered Smart Textiles for Accelerated Wound Healing through Band Alignment in Piezoelectric Heterojunctions

Résumé fourni par la source

Infected foot wounds often exhibit markedly prolonged healing due to local ischemia, multidrug-resistant pathogens, and chronic inflammation, representing a major clinical challenge. This work reports a piezoelectric heterojunction-based smart textile dressing, in which the heterostructure was constructed via atomic layer deposition (ALD) to achieve precise band-structure engineering. By tailoring the number of ZnO deposition cycles on BaTiO 3, the optimized BaTiO 3 -10ZnO heterojunction (10 ALD cycles) exhibits the most favorable band alignment and a 2.95-fold boost in ROS generation efficiency compared with pristine BaTiO 3 . The composite is covalently immobilized onto textile fibers via amine-aldehyde condensation, yielding an intelligent textile platform. In a rat plantar infection model, the dressing, activated by walking-triggered mechanical pressure, achieves the most prominent therapeutic outcome, outperforming other ALD-cycle variants and commercial Ag + dressings. Systematic histological and transcriptomic analyses further unveil its multipronged antibacterial mechanisms, including bacterial membrane disruption, metabolic interference, and oxidative-stress induction. This work offers an innovative strategy for self-powered antimicrobial systems and demonstrates great potential for chronic wound management.

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