Reducing Motion Artifact in High Resolution 7 T MRI Using the Magnetic Resonance Minimal Motion (“MR‐MinMo”) Head Stabilization Device

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PURPOSE: To evaluate the effectiveness of the MR-MinMo head stabilization device in mitigating motion artifacts during long-duration, high-resolution 7 T MRI scans, with and without retrospective motion correction METHODS: The MR-MinMo was tested on seven pediatric and 12 adult healthy volunteers using 0.6 mm isotropic, 3D Multi-Echo Gradient Echo (ME-GRE) scans. A ∼10-min ME-GRE scan (linear sampling acceleration factor 2 × 2) and a ∼20-min scan (DISORDER sampling acceleration factor 1.4 × 1.4) were obtained. Both scans were acquired with and without the MR-MinMo in a 2 × 2 factorial study design. Qualitative and quantitative assessment of image quality of the first echo image was obtained via visual inspection and the normalized gradient squared (NGS) metric, respectively. A repeated measures ANOVA was used to determine individual and combined effects of the device and DISORDER images with retrospective motion correction on NGS values, with age as a binary factor (pediatric/adult). T2* maps were generated and the standard deviation of white matter R2*(=1/T2*) values assessed across conditions. RESULTS: The MR-MinMo significantly reduced motion artifacts both visually and in terms of NGS scores, particularly in pediatric volunteers. There was a significant interaction between MR-MinMo and DISORDER motion correction, suggesting that MR-MinMo improved retrospective motion correction. T2* maps demonstrated improved visual appearance and reduced WM variance with the MR-MinMo. CONCLUSION: The MR-MinMo can improve image quality via motion reduction in high-resolution 7 T scans. By keeping motion within a correctable regime, the device can also improve the performance of retrospective motion correction methods.

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