Dataset for 'Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice'

Le résumé fourni par la source

This dataset contains the raw data supporting main Figures 1-5 and Extended Data Figures 1-10 used in the manuscript "Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice" submitted to Nature Communications. The dataset includes antibody titers in the serum and bronchoalveolar lavage fluid of mice immunized with SARS-CoV-2 mRNA or chimpanzee adenoviral-vectored vaccines at various regimens. The dataset also includes pseudovirus neutralization results and flow cytometry analysis of vaccinated mice. Vaccinations were conducted in wild-type C57BL/6J mice or animals expressing human ACE2 (K18-hACE2 mice). Neutralization assays were performed using Vero cells overexpressing TMPRSS2.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.