Integrated Microfluidic System for Counting and Passive Sorting of Magnetic Hydrogel Microparticles Based on AC Magnetic Susceptibility Detection
Rattachement africain : cn, Afrique du Sud. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
This paper proposes an integrated microfluidic system that can identify, count, prepare, and sort magnetic hydrogel microparticles using alternating current (AC) magnetic susceptibility measurements. The integrated microfluidic system was composed of a microplanar coil for AC magnetic susceptibility measurements and a multifunctional microfluidic chip above the coil. Through the flow-focusing method, Fe 3 O 4 /PEGDA (Fe 3 O 4 /polyethylene glycol diacrylate) magnetic hydrogel microdroplets were generated in a microchannel, then passed over a microplanar coil, and then magnetized to generate a stray field. The strength of the stray field was related to the AC magnetic susceptibility and changed the coil’s induced voltage. By detecting the voltage change, the magnetic hydrogel microparticles could be accurately identified and counted. Furthermore, magnetic hydrogel microparticles with sufficient magnetic content were passively separated from nonmagnetic or weakly magnetic particles using a gradient magnetic field. The system integrated the preparation, identification, counting, and sorting of magnetic hydrogel microparticles and also realized AC magnetic susceptibility measurements, which is difficult to accomplish using other methods. This system shows great potential for biomedical testing and drug-carrying engineering applications, as the ability to identify and count magnetic hydrogel microparticles based on their AC magnetic susceptibility enables precise determination of drug dosage in targeted delivery, while the passive separation of particles with sufficient magnetic content from nonmagnetic or weakly magnetic ones using a gradient magnetic field allows for controlled release and targeted accumulation of therapeutic carriers.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Integrated Microfluidic System for Counting and Passive Sorting of Magnetic Hydrogel Microparticles Based on AC Magnetic Susceptibility Detection
- Date Crossref
- 08/05/2026
- Éditeur
- American Chemical Society (ACS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Zhengzhou University pays non établi dans la noticeUniversité ou école supérieure
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North China University of Water Resources and Electric Power pays non établi dans la noticeUniversité ou école supérieure
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University of Johannesburg Mechanical Engineering Science University of Johannesburg, Afrique du Sud (code pays fourni par la source)Université ou école supérieure
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Shihezi University pays non établi dans la noticeUniversité ou école supérieure
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Henan Province Engineering Technology Research Center of MEMS Manufacturing and Applications. School of Mechanics and Safety Engineering pays non établi dans la noticeUniversité ou école supérieure
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Zhengzhou V3 biotechnology Co. Ltd pays non établi dans la noticeEntreprise
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School of Mechanical Engineering pays non établi dans la noticeUniversité ou école supérieure
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Institute of Bingtuan Energy Development Research pays non établi dans la noticeStructure de recherche
Zhengzhou University, North China University of Water Resources and Electric Power et Mechanical Engineering Science — University of Johannesburg (University of Johannesburg, Afrique du Sud), avec 5 autres affiliations. Pays d’affiliation : Afrique du Sud.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.