Characterizing Relationships Between Daily Pain, Opioid Use, and Mood in Patients With Advanced Cancer Using Ecological Momentary Assessments
Rattachement africain : us, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
PURPOSE In advanced cancer, pain symptoms, opioid use, and cognitive-emotional processes fluctuate day to day and may mutually reinforce one another. We used 28-day ecological momentary assessments (EMAs) to quantify within-person associations between daily pain and (a) interference, (b) opioid use and perceived efficacy, and (c) mood, and to test whether variability in pain catastrophizing moderates these associations. METHODS Patients with advanced cancer receiving outpatient oncology care at a comprehensive cancer center completed once-daily EMAs for 28 days (N = 26 analyzed). Measures included worst/average/least pain, pain interference, short-acting opioid tablets (count) and perceived opioid efficacy, negative and positive affect, and daily catastrophizing. Multilevel models estimated same-day within-person associations, controlling for study day and between-person mean pain. Individuals' standard deviation of daily catastrophizing changes (catastrophizing variability) was tested as a moderator. RESULTS Across 477 daily assessments (median 21/28 per participant), higher-than-usual worst pain was consistently associated with worse pain interference, higher short-acting opioid use, lower perceived opioid efficacy, and higher negative affect (all P < .01); Average and least pain showed smaller or nonsignificant effects. Greater day-to-day variability in catastrophizing was associated with worse pain. Among individuals whose pain catastrophizing fluctuated more, there was a stronger relationship between pain severity and interference, affect, and perceived opioid efficacy (inverse; P ≤ .01). CONCLUSION Greater day-to-day fluctuations in pain catastrophizing were associated with magnified correspondence of pain severity with interference, mood disruption, and perceived opioid inefficacy. Routine monitoring of pain severity combined with tracking catastrophizing variability may help identify high-risk days and inform in-the-moment support to better personalize pain management.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Characterizing Relationships Between Daily Pain, Opioid Use, and Mood in Patients With Advanced Cancer Using Ecological Momentary Assessments
- Date Crossref
- 05/05/2026
- Éditeur
- American Society of Clinical Oncology (ASCO)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Harvard University pays non établi dans la noticeUniversité ou école supérieure
-
Dana-Farber Cancer Institute Department of Supportive Oncology pays non établi dans la noticeStructure de recherche
-
University of Southern California Department of Psychology pays non établi dans la noticeUniversité ou école supérieure
-
University of Oklahoma Health Sciences Center Health Promotion Research Center pays non établi dans la noticeÉtablissement de santé
-
Brigham and Women's Hospital Department of Anesthesiology pays non établi dans la noticeÉtablissement de santé
-
Spaulding Rehabilitation Hospital Department of Physical Medicine and Rehabilitation pays non établi dans la noticeÉtablissement de santé
-
University of Alabama at Birmingham Department of Anesthesiology and Perioperative Medicine pays non établi dans la noticeUniversité ou école supérieure
-
University of Leeds Leeds Institute of Health Sciences pays non établi dans la noticeUniversité ou école supérieure
-
Harvard Medical School pays non établi dans la noticeInstitution
Harvard University, Department of Supportive Oncology — Dana-Farber Cancer Institute et Department of Psychology — University of Southern California, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.