Educational films for improving perinatal outcomes associated with gestational diabetes in Uganda and India: a cluster randomised trial
Rattachement africain : no, gb, in, Ouganda, us, qa. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
INTRODUCTION: Gestational diabetes mellitus (GDM) is associated with a high risk of adverse perinatal outcomes. We evaluated whether a film-based educational intervention for pregnant women and healthcare providers to improve timely detection and management of GDM could reduce the incidence of adverse perinatal outcomes. METHODS: Two parallel-group cluster randomised trials were conducted in Uganda and India. A package of 7 interconnected culturally-tailored educational films was developed following formative research. 30 government-funded health facilities (clusters) in each country were randomised (1:1) to intervention or control arm. In intervention facilities (15 in each country), films were shared with pregnant women and health professionals; control facilities (15 in each country) received usual care. The outcome was an individual self-reported composite of unplanned caesarean section, stillbirth or neonatal death, or neonatal hospitalisation. Mixed effects models were used in an intention-to-treat analysis with multiple imputation by chained equations to address missing data. Analyses were performed separately for each country; random-effects meta-analysis was used to calculate pooled prevalence ratios (PRs). Data analysts were blinded to group allocation, but participants, facility and trial staff were not. RESULTS: In Uganda, 5495 women were screened between May 2021 and April 2022, and 5102 (92.8%) participated in the trial. In India, 12 045 women were screened between July 2021 and January 2022, and 10 899 (90.5%) participated. Loss to follow-up was 31.7% in Uganda and 12.1% in India. In Uganda, the prevalence of the composite adverse perinatal outcome was 19.7% in the control arm and 19.8% in the intervention arm (PR 1.00, 95% CI 0.87 to 1.14). For India, the prevalence was 29.5% and 30.6%, respectively (PR 1.04, 95% CI 0.96 to 1.11). The pooled PR across both countries was 1.03 (95% CI 0.97 to 1.10). CONCLUSIONS: A film-based intervention did not reduce the incidence of adverse perinatal outcomes associated with GDM. Future evaluations should assess educational films delivered alongside more intensive intervention components. TRIAL REGISTRATION NUMBERS: NCT03937050, ISRCTN96432637.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Educational films for improving perinatal outcomes associated with gestational diabetes in Uganda and India: a cluster randomised trial
- Date Crossref
- 01/04/2026
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Norwegian Institute of Public Health Centre for Fertility and Health pays non établi dans la noticeOrganisme public
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London School of Hygiene & Tropical Medicine Department of Non-Communicable Disease Epidemiology pays non établi dans la noticeUniversité ou école supérieure
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Institute of Public Health Bengaluru pays non établi dans la noticeOrganisation à but non lucratif
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Public Health Foundation of India pays non établi dans la noticeOrganisation à but non lucratif
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MRC/UVRI & LSHTM Uganda Research Unit Ouganda (code pays fourni par la source)Structure de recherche
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Uganda Virus Research Institute Ouganda (code pays fourni par la source)Structure de recherche
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Harvard University Department of Biostatistics pays non établi dans la noticeUniversité ou école supérieure
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Cancer Research And Biostatistics pays non établi dans la noticeOrganisation à but non lucratif
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King's College London Division for Care in Long Term Conditions pays non établi dans la noticeUniversité ou école supérieure
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Guy's and St Thomas' NHS Foundation Trust Department of Women’s Health pays non établi dans la noticeÉtablissement de santé
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Qatar University Department of Population Medicine pays non établi dans la noticeUniversité ou école supérieure
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Indian Institute of Public Health pays non établi dans la noticeStructure de recherche
Centre for Fertility and Health — Norwegian Institute of Public Health, Department of Non-Communicable Disease Epidemiology — London School of Hygiene & Tropical Medicine et Institute of Public Health Bengaluru, avec 9 autres affiliations. Pays d’affiliation : Ouganda.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.