Esophageal cancer related mortality among cancer admissions at Livingstone University Teaching Hospital southern province Zambia
Rattachement africain : Afrique du Sud, Zambie, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Esophageal cancer (EC) is a major cause of cancer-related mortality globally, with low- and middle-income countries (LMICs) disproportionately affected due to late-stage diagnoses and limited treatment access. In Sub-Saharan Africa, particularly the “esophageal cancer belt” that includes Zambia, incidence and mortality rates are among the highest worldwide. Within Zambia, the Southern and Eastern Provinces have seen rising EC cases. Despite frequent presentations at Livingstone University Teaching Hospital (LUTH), local data on EC-related mortality remains limited. This study aimed to determine the proportion of esophageal cancer (EC)–related deaths at Livingstone University Teaching Hospital (LUTH) and identify factors associated with mortality among patients diagnosed with cancer. A retrospective cross-sectional study was conducted using medical records of 212 adults admitted with any cancer diagnosis at Livingstone University Teaching Hospital (LUTH) between January 2023 and December 2024. The proportion of deaths attributable to esophageal cancer was assessed among all cancer patients. Sociodemographic and clinical data were collected through a standardized form. Descriptive analyses were performed, and multivariable logistic regression was employed to identify factors associated with mortality. Among the 212 individuals hospitalized with cancer, 53.1% were male ( n = 112), with a median age of 63.5 years (IQR: 50–72 years). The proportion of EC-related deaths was 11.3% ( n = 24) (95% CI 7.3%–16.3%), with males accounting for 75% of the deaths ( n = 18). HIV-positive status (adjusted odds ratio [aOR] = 4.61; 95% CI 1.67–12.76; p = 0.003) and smoking (aOR = 6.79; 95% CI 2.30–20.07; p < 0.001) were significantly associated with mortality. EC continues to contribute significantly to cancer mortality at LUTH. HIV coinfection and smoking were strong predictors of death. Strengthening esophageal cancer surveillance among people living with HIV and promoting targeted tobacco cessation interventions, particularly among males, may support efforts to reduce mortality in high-burden settings.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Esophageal cancer related mortality among cancer admissions at Livingstone University Teaching Hospital southern province Zambia
- Date Crossref
- 25/04/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Livingstone Hospital Afrique du Sud (code pays fourni par la source)Établissement de santé
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Mulungushi University Department of Pathology Zambie (code pays fourni par la source)Université ou école supérieure
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Zambia Forestry College Zambie (code pays fourni par la source)Université ou école supérieure
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Livingstone College pays non établi dans la noticeUniversité ou école supérieure
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Livingstone Center for Prevention and Translational Science Zambie (code pays fourni par la source)Organisation à but non lucratif
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Livingstone University Teaching Hospital Department of Surgery Zambie (pays nommé en fin d’affiliation)Université ou école supérieure
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Kitwe University Teaching Hospital Kitwe University Teaching Hospital, Zambie (pays nommé en fin d’affiliation)Université ou école supérieure
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Division of Integrated Sciences Zambie (pays nommé en fin d’affiliation)Institution
Livingstone Hospital (Afrique du Sud), Department of Pathology — Mulungushi University (Zambie) et Zambia Forestry College (Zambie), avec 5 autres affiliations. Pays d’affiliation : Afrique du Sud, Zambie.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.