PATHY-inspired partial tumor irradiation on a small-animal irradiator: workflow development and first therapeutic evaluation in glioma

Le résumé fourni par la source

This repository contains the source data supporting the survival and dosimetric results reported in the manuscript: PATHY-inspired partial tumor irradiation on a small-animal irradiator: workflow development and first therapeutic evaluation in glioma.The survival data include anonymized individual animal survival outcomes for each experimental group. Kaplan–Meier survival curves and statistical analyses were performed using GraphPad Prism. The dosimetry data include radiochromic film (RCF) measurements used for dosimetric evaluation and quality assurance of the irradiation workflow. The treatment/irradiation summary table describes the experimental group, dose regimen, fractionation schedule, and irradiation parameters for each animal. The repository also includes a representative contoured MRI example and MuriPlan treatment-planning screenshot. This representative image is provided to document the contouring approach and does not represent the complete imaging dataset.The MuriPlan screenshot shows the PATHY-inspired partial tumor irradiation setup, with two 1 mm collimated orthovoltage beams delivered at gantry 90° to two isocenters positioned within the geometrically defined tumor core, and the corresponding isodose distribution overlaid on the rat brain CBCT.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.