Antibiotic Resistance Gene detection on the Global Microbial Gene Catalog

Résumé fourni par la source

This dataset supports the results presented in the manuscript: The elusive resistome: a global comparison reveals large discrepancies among detection pipelines. It contains antibiotic resistance gene (ARG) detection results from unigenes in the Global Microbial Gene Catalog v1.0 (GMGC) using multiple widely used detection pipelines (including DeepARG, RGI, fARGene, ResFinder, AMRFinderPlus, and ABRicate with multiple databases). Outputs were harmonized using argNorm and manually curated, estimations of ARG abundance and richness as well as pan- and core-resistome were done across 11,519 metagenomic samples spanning 13 habitats (human-associated, animal-associated, and environmental), at the ARG class level. This resource supports comparative analyses of how ARG detection pipelines influence resistome interpretation.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.