Association between physical activity and knee osteoarthritis in community-dwelling Japanese adults: an 11-year cohort study
Rattachement africain : jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Evidence on factors influencing the association between physical activity (PA) and knee osteoarthritis (KOA) is scarce. The present study aimed to examine this association and explore interactions of PA with sex and age in relation to KOA in Japanese adults. METHODS: This 11-year cohort study included 10,876 community-dwelling individuals aged 40-74 years in Murakami City (Niigata Prefecture, Japan). Data were collected using a self-administered questionnaire (2011-2013). Exposures were self-reported PA levels, and the outcome was clinically diagnosed KOA. Covariates included demographic factors, body size, lifestyle habits, and disease history. Cox proportional hazards models were used to estimate hazard ratios (HRs). RESULTS: The mean age of participants was 58.0 years. Over a mean follow-up period of 11.1 years, 840 cases of KOA were observed. High total PA levels were associated with a greater KOA risk (P for trend <0.0001), with the highest quartile showing a higher hazard (HR=1.52, 95%CI:1.23-1.87) than the lowest (reference). This association was observed in both males (HR=2.01, 95%CI:1.39-2.93) and females (HR=1.30, 95%CI:1.01-1.66), with a P for interaction of 0.0219. In addition, the association was more pronounced in younger participants (<55 years; HR=2.07, 95%CI:1.25-3.43) and attenuated in older age groups, with a P for interaction of 0.0278. Non-leisure-time PA showed a similar association with KOA as total PA, whereas leisure-time PA did not. CONCLUSION: High total and non-leisure-time PA levels were associated with increased KOA risk, and these associations interacted with sex and age in middle-aged Japanese adults.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Association between physical activity and knee osteoarthritis in community-dwelling Japanese adults: an 11-year cohort study
- Date Crossref
- 01/01/2026
- Éditeur
- Japan Epidemiological Association
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Niigata University Division of Preventive Medicine pays non établi dans la noticeUniversité ou école supérieure
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Niigata University of Rehabilitation pays non établi dans la noticeUniversité ou école supérieure
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Chiba Prefectural Government pays non établi dans la noticeOrganisme public
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Niigata Prefectural Government pays non établi dans la noticeOrganisme public
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Nara Women's University Department of Food Science and Nutrition pays non établi dans la noticeUniversité ou école supérieure
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International University of Health and Welfare pays non établi dans la noticeUniversité ou école supérieure
Division of Preventive Medicine — Niigata University, Niigata University of Rehabilitation et Chiba Prefectural Government, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.