Optimising sleep and managing stress by integrating a behavioural intervention during cardiac rehabilitation: rationale and design of the OPTICARE-RESST multicentre randomised controlled trial
Rattachement africain : nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
INTRODUCTION: Over 50% of patients participating in cardiac rehabilitation (CR) experience poor sleep and/or, closely related, psychological stress. Although stress management interventions are generally available, they are typically underutilised in CR, and sleep remains an underaddressed component within CR. This is concerning, as poor sleep and stress not only reinforce each other but are also associated with poorer cardiovascular health and lower quality of life. Therefore, the primary aim of the OPtimising CArdiac REhabilitation by REfining Sleep and STress (RESST) study is to investigate the (cost-)effectiveness of adding a behavioural intervention targeted at improving sleep and managing stress during CR (RESST intervention) on sleep and psychological stress. Furthermore, the study aims to explore the (bidirectional) associations between sleep, stress and lifestyle behaviours. METHODS AND ANALYSIS: This parallel-arm multicentre randomised controlled trial will include 200 CR patients across 3 major CR centres in the Netherlands who experience poor sleep and/or stress. Patients will be randomised in a 1:1 ratio to standard CR or standard CR with the RESST intervention. Standard CR is a structured programme combining exercise, lifestyle guidance and risk management. On top of standard CR, the RESST intervention consists of 5 in-person group sessions targeting sleep and stress and is based on Acceptance and Commitment Therapy and Cognitive Behavioural Therapy. Primary outcomes are accelerometer-assessed and self-reported sleep and perceived stress. Secondary outcomes include quality of life, psychosocial well-being, chronic stress biomarkers (hair cortisol and cortisone), momentary fatigue, momentary stress and physical activity. Linear mixed models will be used to assess changes in outcomes at 3-month (after intervention and/or CR completed) and 6-month follow-up. The momentary data collected with ecological momentary assessment and accelerometry will be analysed using multilevel linear mixed models to explore the (bidirectional) relationship between sleep, stress and other lifestyle components such as physical activity. ETHICS AND DISSEMINATION: This study was approved by the ethics committee of Erasmus MC, Erasmus University Medical Centre, Rotterdam, the Netherlands (MEC-2024-0238). The findings will be disseminated through publications in peer-reviewed journals, presentations at academic conferences and professional and patient publications. TRIAL REGISTRATION NUMBER: NCT06505109.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Optimising sleep and managing stress by integrating a behavioural intervention during cardiac rehabilitation: rationale and design of the OPTICARE-RESST multicentre randomised controlled trial
- Date Crossref
- 01/04/2026
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Erasmus MC Department of Rehabilitation Medicine pays non établi dans la noticeÉtablissement de santé
-
Capri Hartrevalidatie pays non établi dans la noticeÉtablissement de santé
-
Trimbos Institute pays non établi dans la noticeStructure de recherche
-
Radboud University Nijmegen pays non établi dans la noticeUniversité ou école supérieure
-
Máxima Medisch Centrum pays non établi dans la noticeÉtablissement de santé
-
Erasmus University Rotterdam pays non établi dans la noticeUniversité ou école supérieure
-
Erasmus MC - Sophia Children’s Hospital pays non établi dans la noticeÉtablissement de santé
-
Capri Cardiac Rehabilitation pays non établi dans la noticeInstitution
-
The Netherlands Institute of Mental Health and Addiction pays non établi dans la noticeStructure de recherche
-
Department of Cardiology pays non établi dans la noticeInstitution
-
Erasmus School of Health Policy and Management pays non établi dans la noticeUniversité ou école supérieure
-
University Medical Centre Rotterdam Department of Neonatal and Pediatric Intensive Care pays non établi dans la noticeUniversité ou école supérieure
Department of Rehabilitation Medicine — Erasmus MC, Capri Hartrevalidatie et Trimbos Institute, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.