Recommendations and guidance for pneumococcal vaccination for adults in Taiwan
Rattachement africain : tw. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Streptococcus pneumoniae remains a global health concern, causing diseases from sinusitis, otitis media, to invasive pneumococcal diseases (IPD), such as bacteremia, bacteremic pneumonia, empyema, and meningitis. Key IPD risk factors include age under five or over 50 years, chronic medical conditions, and lifestyle factors. In Taiwan, IPD incidence has declined following national immunization program. However, morbidity and mortality remain substantial, particularly among older adults. There are two types of pneumococcal vaccines, polysaccharide conjugate vaccines (PCV) and pneumococcal polysaccharide vaccines (PPSV). These vaccines target specific IPD serotypes but may lead to serotype replacement. In Taiwan, the available/forthcoming vaccines include PCV13, PCV15, PCV20, PCV21, and PPSV23, with numbers indicating serotype coverage. This guidance, developed and endorsed by eight national academic societies, serves as an adjunct to the Taiwan Advisory Committee on Immunization Practices recommendations. Using the GRADE framework, it provides evidence-based recommendations for adult pneumococcal vaccination. It emphasizes health promotion to assist healthcare professionals in vaccine selection tailored to current local epidemiology and individual vaccination history. A shared decision-making approach is encouraged, considering individual vulnerabilities, exposure risks, and lifestyle factors. This guidance addresses optimal timing, dosing schedules, coadministration, and safety; grounded in immunological evidence on efficacy, effectiveness, and immunogenicity. In recognition of feasibility of implementation, single-dose PCV20 or PCV21 is proposed as a simplified alternative to complex sequential strategies. However, PCV21 is recommended only where PCV7 serotypes are well controlled or no longer prevalent. This guidance reflects evolving pneumococcal vaccination strategies in response to serotype dynamics and availability of higher-valency conjugate vaccines.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Recommendations and guidance for pneumococcal vaccination for adults in Taiwan
- Date Crossref
- 01/06/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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I-Shou University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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National Taiwan University Hospital Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Taichung Veterans General Hospital Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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National Cheng Kung University Hospital Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Taipei Veterans General Hospital Department of Pediatrics pays non établi dans la noticeÉtablissement de santé
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National Defense Medical Center pays non établi dans la noticeÉtablissement de santé
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National Yang Ming Chiao Tung University pays non établi dans la noticeUniversité ou école supérieure
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Chang Gung University Molecular Infectious Disease Research Center pays non établi dans la noticeUniversité ou école supérieure
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Fu Jen Catholic University pays non établi dans la noticeUniversité ou école supérieure
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Mackay Memorial Hospital pays non établi dans la noticeÉtablissement de santé
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Kaohsiung Veterans General Hospital Department of Pediatrics pays non établi dans la noticeOrganisme public
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Cathay General Hospital Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
Department of Internal Medicine — I-Shou University, Department of Internal Medicine — National Taiwan University Hospital et Department of Internal Medicine — Taichung Veterans General Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.