Additional file 1 of Onchocerca volvulus infection prevalence and intensity in Logo and Nyarambe Health Zones in Ituri, Democratic Republic of the Congo in 2010 and in 2021–2023: results of screening for clinical trials of moxidectin versus ivermectin

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Supplementary Material 1. Table S1 GPS coordinates for villages in which individuals were screened in 2010 and/or 2021-2023. Fig. S1 Aires de Santé where participants lived with dwelling and major roadways in 2021-2023. Fig. S2 Overview of study area. Fig. S3 Photos of study area taken in 2022–2024 by T.O. Ukety and F.N. Nyisis. Table S2 Results of the rapid epidemiological assessment conducted in 2002 as per the site-level ESPEN database (accessed on 14 September 2024) with current Zone and Aire de Santé and APOC CDTI Project. Fig. S4 Map of 2002 rapid epidemiological assessment results. Table S3 CRMT capacities, research experience, and diseases in the area. Fig. S5 Percentage and number of individuals screened (lower panel) by age screened in 2010 and 2021–2023 in ZdS Logo and in 2021–2023 in the ZdS Nyarambe. Fig. S6 Skin microfilariae density among all women and men (A) screened in 2010, and women (B) and men (C) screened in 2021–2023 who had no prior ivermectin treatment and (D) women and men reporting ivermectin treatment between 2 and 1800 days before screening in ZdS Nyarambe. Table S4 Number of participants without prior IVM treatment screened in 2010 and 2021-2023 by age group, gender, and skin microfilariae density category by Zone de Santé. Table S5 Number of adults and adolescents without prior ivermectin treatment screened in 2010 and in 2021–2023 with and without detectable SmfD. Fig. S7 Skin microfilariae density among volunteers in the 10 villages where at least 20 individuals without prior ivermectin treatment were screened in 2010 and in 2021–2023 by age and gender. Table S6 Descriptive statistics of SmfD for mf-positive individuals without prior ivermectin treatment screened in 2010 and in 2021–2023. Table S7 Publicly available data on onchocerciasis prevalence in and around the Zone de Santés Nyarambe and Logo. Table S8 Prevalence of O. volvulus infection by village based on skin mf densities from only the two iliac crests. References. Abbreviations.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.