Prophylactic transarterial embolization after endoscopic hemostasis in patients with non-variceal upper gastrointestinal bleeding - is it time to act?
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Non-variceal upper gastrointestinal bleeding (NVUGIB) continues to present a significant clinical burden due to rebleeding after apparently successful endoscopic hemostasis, particularly in ulcers overlying large-caliber arterial territories. Prophylactic transarterial embolization (pTAE) has been proposed as a strategy to prevent rebleeding in high-risk patients. This mini-review evaluates the evidence for pTAE after successful endoscopic control in NVUGIB, focusing on patient selection, technical approaches, outcomes, and complications. Methods: A literature search of PubMed and Scopus (January 2010-September 2025) was conducted, yielding 10 studies (two randomized trials, three prospective, and five retrospective) evaluating pTAE. Only studies addressing prophylactic, not empiric, embolization were included. Results: Evidence suggests that pTAE is technically feasible and generally safe when guided by ulcer location, size (≥15-20 mm), Rockall score (≥5), and arterial territory (GDA or LGA). While randomized trials did not show overall superiority in intention-to-treat analyses, per-protocol data and observational studies suggest reduced rebleeding and a lower need for surgical rescue in well-selected patients. Complications are infrequent when standardized techniques and early timing (≤24 h) are applied. Conclusion: Routine pTAE is not supported by current guidelines or RCT-level evidence. However, in anatomically and clinically high-risk ulcers, pTAE may offer meaningful benefits. Further multicenter randomized trials with uniform protocols are warranted to clarify its role and optimize patient selection.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prophylactic transarterial embolization after endoscopic hemostasis in patients with non-variceal upper gastrointestinal bleeding - is it time to act?
- Date Crossref
- 02/04/2026
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Magna Graecia University pays non établi dans la noticeUniversité ou école supérieure
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Azienda Ospedaliero Universitario Mater Domini pays non établi dans la noticeÉtablissement de santé
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Azienda USL di Bologna pays non établi dans la noticeÉtablissement de santé
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University Hospital Policlinico “G. Rodolico-San Marco” Department of Medical Surgical Sciences and Advanced Technologies “GF Ingrassia” pays non établi dans la noticeUniversité ou école supérieure
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University Hospital Mater Domini Department of Experimental and Clinical Medicine pays non établi dans la noticeUniversité ou école supérieure
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Department of Radiology pays non établi dans la noticeInstitution
Magna Graecia University, Azienda Ospedaliero Universitario Mater Domini et Azienda USL di Bologna, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.