Efficient oxidative spirolactamization by μ-oxo bridged heterocyclic hypervalent iodine compound

Le résumé fourni par la source

In this report, the authors have clarified that the μ-oxo bridged heterocyclic hypervalent iodine compound 1 shows a more effective reactivity in the oxidative dearomatizing spirolactamization compared to conventional PIDA (phenyliodine(III) diacetate). Besides the high reactivity, a new selectivity during the oxidations based on the steric discrimination of the nitrogen groups of the pre-spirocyclic substrates is demonstrated for the heterocyclic hypervalent iodine compound 1. © 2014 The Japan Institute of Heterocyclic Chemistry.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.