調整前後の精子所見が子宮内人工授精の成績に及ぼす影響

Le résumé fourni par la source

Purpose: To examine the association between semen characteristics and outcomes of intrauterine insemination (IUI).Methods: This retrospective analysis examined 1380 IUI procedures involving 421 couples.The association of clinical pregnancy with pre-and post-wash sperm characteristics was assessed.Results: Pre-and post-wash sperm characteristics did not differ between IUI cycles that resulted in pregnancy and those that did not.When the motility of prewash sperm was below the normal range (<42%) established by the World Health Organization (WHO), the pregnancy rate was significantly lower.In the IUI cycles when post-wash sperm motility was below the WHO standard, pregnancy was not achieved.The frequency of improvement in post-wash sperm motility in repeated IUI cycles appeared to correlate with the success of future IUI cycles.At the fourth IUI cycle, pregnancy was not achieved unless the post-wash sperm motility was normal in at least two of three attempts.When post-wash sperm concentration was below the normal range, the woman's age did not affect the IUI outcomes.Conclusions: Sperm motility above the lower limit of the WHO criteria in post-wash semen samples is an important factor in IUI outcomes.

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