A solid-phase click$^2$ strategy for chromophore–DNA conjugates and their application as a light harvesting system

Le résumé fourni par la source

A stepwise and orthogonal approach of two independent click reactions directly on the solid phase gives easy access to doubly modified DNA. Firstly, 5′-ethynyl-2′-deoxyuridine reacts directly with an azide-modified porphyrin; secondly, 5′-azido-2′-deoxyuridine is generated in situ from 5′-iodo-2′-deoxyuridine, which enables a click reaction with an alkyne-functionalized pyrene. The doubly modified DNA was characterized as a light-harvesting system.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.