obophenotype/cell-ontology: 2026-03-26 Release

Le résumé fourni par la source

Release Notes 2026-03-26 Ontology content summary | Metric | Value | |:------------------------------------------------|--------:| | Number of subclasses of root | 3314 | | Number of annotations on CL terms | 17396 | | Number of synonyms | 7125 | | Number of unique references | 1960 | | Number of unique references in definitions | 2079 | | Number of relationships with CL term as subject | 5109 | | Number of cellxgene classes | 1026 | | Number of HRA classes | 616 | Nodes added to subset: 4 | Term | Subset | ----|----| | osteoblast (CL:0000062) | human_reference_atlas | | chondrocyte (CL:0000138) | human_reference_atlas | | obsolete female germ line stem cell (sensu Vertebrata) (CL:0000090) | human_reference_atlas | | mesenchymal stem cell (CL:0000134) | human_reference_atlas | Classes added: 8 | Term | ----| | tuft cell of parotid gland (CL:0020063) | | serous demilune cell of salivary gland (CL:0020059) | | basal duct cell of salivary gland (CL:0020060) | | ionocyte of salivary gland (CL:0020065) | | junctional epithelial cell (CL:0020062) | | tuft cell of sublingual gland (CL:0020064) | | periductal fibroblast of salivary gland (CL:0020061) | | myoepithelial cell of salivary gland (CL:0020066) | Relationships added: 25 | Subject | Predicate | Object| ----|----|----| | junctional epithelial cell (CL:0020062) | subClassOf (rdfs:subClassOf) | stratified epithelial cell (CL:0000079) | | serous acinar cell of salivary gland (CL:4052065) | subClassOf (rdfs:subClassOf) | serous demilune cell of salivary gland (CL:0020059) | | junctional epithelial cell (CL:0020062) | RO:0002215 | GO:0002227 | | serous demilune cell of salivary gland (CL:0020059) | subClassOf (rdfs:subClassOf) | exocrine cell (CL:0000152) | | junctional epithelial cell (CL:0020062) | BFO:0000050 | UBERON:0001949 | | ionocyte of salivary gland (CL:0020065) | RO:0002215 | GO:0050801 | | tuft cell of sublingual gland (CL:0020064) | subClassOf (rdfs:subClassOf) | tuft cell (CL:0002204) | | myoepithelial cell of salivary gland (CL:0020066) | RO:0002215 | GO:0006939 | | basal duct cell of salivary gland (CL:0020060) | BFO:0000050 | UBERON:0001837 | | myoepithelial cell of salivary gland (CL:0020066) | subClassOf (rdfs:subClassOf) | myoepithelial cell (CL:0000185) | | ionocyte of salivary gland (CL:0020065) | BFO:0000050 | UBERON:0001044 | | myoepithelial cell of salivary gland (CL:0020066) | BFO:0000050 | UBERON:0001044 | | periductal fibroblast of salivary gland (CL:0020061) | subClassOf (rdfs:subClassOf) | fibroblast (CL:0000057) | | periductal fibroblast of salivary gland (CL:0020061) | BFO:0000050 | UBERON:0001044 | | basal duct cell of salivary gland (CL:0020060) | subClassOf (rdfs:subClassOf) | basal cell (CL:0000646) | | tuft cell of parotid gland (CL:0020063) | BFO:0000050 | UBERON:0001831 | | junctional epithelial cell (CL:0020062) | subClassOf (rdfs:subClassOf) | ecto-epithelial cell (CL:0002077) | | junctional epithelial cell (CL:0020062) | subClassOf (rdfs:subClassOf) | epithelial cell of alimentary canal (CL:0002251) | | ionocyte of salivary gland (CL:0020065) | subClassOf (rdfs:subClassOf) | ionocyte (CL:0005006) | | tuft cell of sublingual gland (CL:0020064) | BFO:0000050 | UBERON:0001832 | | serous demilune cell of salivary gland (CL:0020059) | BFO:0000050 | UBERON:0001044 | | serous demilune cell of salivary gland (CL:0020059) | subClassOf (rdfs:subClassOf) | serous secreting cell (CL:0000313) | | serous demilune cell of salivary gland (CL:0020059) | RO:0002215 | GO:0046541 | | tuft cell of sublingual gland (CL:0020064) | subClassOf (rdfs:subClassOf) | epithelial cell of alimentary canal (CL:0002251) | | tuft cell of parotid gland (CL:0020063) | subClassOf (rdfs:subClassOf) | tuft cell (CL:0002204) | Synonyms added: 18 | Term | New Synonym | Predicate | ----|----|----| | serous demilune cell of salivary gland (CL:0020059) | demilune cell of salivary gland | oio:hasRelatedSynonym | | periductal fibroblast of salivary gland (CL:0020061) | immunofibroblast of salivary gland | oio:hasRelatedSynonym | | myoepithelial cell of salivary gland (CL:0020066) | salivary gland myoepithelial cell | oio:hasExactSynonym | | myoepithelial cell of salivary gland (CL:0020066) | salivary myoepithelial cell | oio:hasExactSynonym | | junctional epithelial cell (CL:0020062) | JE cell | oio:hasExactSynonym | | serous demilune cell of salivary gland (CL:0020059) | Crescents of Giannuzzi | oio:hasRelatedSynonym | | tuft cell of sublingual gland (CL:0020064) | sublingual gland tuft cell | oio:hasExactSynonym | | tuft cell of parotid gland (CL:0020063) | brush cell of parotid gland | oio:hasRelatedSynonym | | serous demilune cell of salivary gland (CL:0020059) | serous crescent cell | oio:hasRelatedSynonym | | periductal fibroblast of salivary gland (CL:0020061) | salivary gland fibroblast | oio:hasBroadSynonym | | junctional epithelial cell (CL:0020062) | gingival junctional epithelial cell | oio:hasRelatedSynonym | | serous demilune cell of salivary gland (CL:0020059) | serous demilune cell | oio:hasExactSynonym | | myoepithelial cell of salivary gland (CL:0020066) | basket cell of salivary gland | oio:hasRelatedSynonym | | tuft cell of parotid gland (CL:0020063) | parotid gland tuft cell | oio:hasExactSynonym | | basal duct cell of salivary gland (CL:0020060) | basal ductal cell of salivary gland | oio:hasExactSynonym | | junctional epithelial cell (CL:0020062) | DAT cell | oio:hasNarrowSynonym | | tuft cell of sublingual gland (CL:0020064) | brush cell of sublingual gland | oio:hasRelatedSynonym | | junctional epithelial cell (CL:0020062) | cell of junctional epithelium | oio:hasExactSynonym | Text definitions added: 8 | Term | New Text Definition | ----|----| | tuft cell of parotid gland (CL:0020063) | A tuft cell that is part of the epithelium of the parotid gland, localized to the striated ducts and never observed in acini. This cell is characterized by expression of POU2F3 and is expected to possess chemosensory function consistent with tuft cells in other tissues. Immunohistochemical analysis of normal human parotid gland tissue detected POU2F3-positive cells as a very rare population within the ductal compartment, positioned on the luminal side (Hoki et al., 2024). | | tuft cell of sublingual gland (CL:0020064) | A tuft cell that is part of the epithelium of the sublingual gland, localized to the ductal compartment. This cell is characterized by expression of POU2F3, consistent with tuft cell identity. Immunohistochemical analysis detected POU2F3-positive cells in normal human sublingual gland tissue (Hoki et al., 2024). | | ionocyte of salivary gland (CL:0020065) | An ionocyte that is part of a salivary gland, localized to the ductal compartment on the luminal side. This specialized epithelial cell is characterized by expression of FOXI1 and is involved in regulating and maintaining osmotic pressure within the glandular environment (Dong et al., 2024). In normal human salivary glands, FOXI1-positive cells constitute less than 5% of ductal epithelial cells and are found exclusively in ducts, never in acini, across all major gland types including parotid, submandibular, sublingual, and minor salivary glands (Hoki et al., 2024). Like ionocytes in other tissues, this cell is expected to express high levels of CFTR and possess abundant mitochondria and ion transporters. | | myoepithelial cell of salivary gland (CL:0020066) | A myoepithelial cell that is part of a salivary gland, positioned between the basal lamina and the secretory or ductal epithelial cells surrounding acini and intercalated ducts. This cell adopts a stellate morphology with four to eight cellular processes around acini and an elongated form parallel to the ductal axis around intercalated ducts (Amano et al., 2012). It expresses alpha-smooth muscle actin (ACTA2/alpha-SMA) as a primary marker, along with p63 and aquaporin 1 (AQP1), and contracts rhythmically in response to neural stimulation to facilitate saliva expulsion from secr

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.