Associations between systemic inflammatory blood biomarkers and intramammary infection caused by Staphylococcus aureus in susceptible and resistant Holstein cows
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Intramammary infections (IMI), especially in their subclinical form, are a major concern in dairy herds due to their impact on udder health and productivity. This study assessed the associations between IMI induced by Staphylococcus aureus and 33 hematobiochemical parameters (inflammation, liver function, metabolism, and oxidative stress) in Holstein cows without clinical signs of disease. Four hundred multiparous cows were selected from a commercial herd based on genetic (estimated breeding values for somatic cell count [SCC]) and phenotypic data (SCC and mastitis history), and classified as resistant (TOP, n = 200) or susceptible (BOTTOM, n = 200) to mastitis. At time 0 (T0), milk cultures identified 37 cows positive for IMI pathogens (27 for S. aureus, 4 for S. dysgalactiae, and 3 for S. uberis) that were bacteriologically monitored also at T1 and T2 (2 and 4 weeks after T0, respectively) and sampled for the hematochemical parameters. Statistical analyses focused on cows infected with S. aureus, the only group with adequate case numbers. Infected cows showed evidence of systemic inflammatory and immune responses, such as increase in serum amyloid A (T1; p = 0.0496) and neutrophil counts (T2; p = 0.0337). Markers of hepatic function were also altered, with higher gamma-glutamyl transferase (T2; p = 0.0125) and aspartate aminotransferase (T2; p = 0.0304) concentrations, suggesting liver involvement during infection. Beta-hydroxybutyrate (T1; p = 0.0172) levels were elevated in infected cows, reflecting energy imbalance. Overall, these findings underscored the value of blood biomarkers for the early detection of affected animals.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Associations between systemic inflammatory blood biomarkers and intramammary infection caused by <i>Staphylococcus aureus</i> in susceptible and resistant Holstein cows
- Date Crossref
- 26/03/2026
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Padua pays non établi dans la noticeUniversité ou école supérieure
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Istituto Zooprofilattico Sperimentale delle Venezie pays non établi dans la noticeÉtablissement de santé
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University of Bologna Department of Agri-Food Science and Technology (DISTAL) pays non établi dans la noticeUniversité ou école supérieure
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Associazione Italiana Sclerosi Multipla pays non établi dans la noticeOrganisation à but non lucratif
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University of Padova Department of Agronomy pays non établi dans la noticeUniversité ou école supérieure
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Associazione Nazionale Allevatori della Razza Frisona pays non établi dans la noticeInstitution
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Federazione delle Associazioni Nazionali di Razza e Specie (FedANA) pays non établi dans la noticeInstitution
University of Padua, Istituto Zooprofilattico Sperimentale delle Venezie et Department of Agri-Food Science and Technology (DISTAL) — University of Bologna, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.