Clinical and patient-centred outcomes following one-anastomosis gastric bypass: A comprehensive evaluation of weight loss, patient satisfaction, quality of life and recommendation rates

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INTRODUCTION: Mini-gastric bypass/one-anastomosis gastric bypass (MGB-OAGB) represents a technical adaptation in bariatric surgery with proven efficacy in weight reduction. However, longitudinal data on weight loss trajectories, patient satisfaction, quality of life (QoL) improvements and willingness to recommend are limited. PATIENTS AND METHODS: We retrospectively analysed 88 adult patients who underwent primary laparoscopic MGB-OAGB from January 2022 to December 2023. Early complications (Clavien-Dindo Grade II or higher) were recorded. At an average follow-up of 9.2 ± 1.8 months, patient-reported outcomes (PROs) were assessed via telephone survey, including reflux symptoms, dietary adherence, satisfaction (Likert scale; ≥4 considered satisfied), QoL change and willingness to recommend. Weight loss was evaluated as excess weight loss percentage (EWL%) and total weight loss percentage (TWL%). Multivariable logistic regression identified predictors of poor patient experience. RESULTS: Baseline body mass index (BMI) averaged 44.7 ± 6.1 kg/m2. The early complication rate was 11.4%. Among 69 respondents, 84.1% reported satisfaction, 88.4% QoL improvement and 81.2% would recommend MGB-OAGB. At 6-12 months, BMI decreased to 30.1 ± 4.9 kg/m2; TWL% was 32.4 ± 7.2 and EWL% was 78.3 ± 13.6. Early complications (odds ratio [OR] 3.2; 95% confidence interval [CI] 1.1-9.4; P = 0.03) and baseline BMI ≥45 kg/m2 (OR 2.8; 95% CI 1.0-7.6; P = 0.04) predicted a poor PRO. CONCLUSIONS: MGB-OAGB provides substantial weight loss, high satisfaction, significant QoL gains and strong patient endorsement at 1 year. Minimising complications and optimising care for patients with elevated BMI may further improve outcomes.

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