WCN26-6465 APPLICATION OF TRF-BUDESONIDE(NEFECON) IN THE TREARMENT OF PEDIATRIC PATIENT WITH IGA NEPHROPATHY: A CASE REPORT

Résumé fourni par la source

Immunoglobulin A nephropathy (IgAN) is one of the most common primary glomerular diseases in children and adolescents, with 20% of affected children progressing to end-stage kidney disease (ESKD) within 20 years of diagnosis. While glucocorticoids are used in adult IgAN to protect renal function, their systemic toxicity is a concern, and there is no consensus on their use in pediatric IgAN due to insufficient evidence and population differences. The pathogenesis of IgAN is not fully understood, but growing evidence highlights the role of the gastrointestinal mucosal immune system.

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