Additional file 2 of Intranasal SARS-CoV-2 infection changes the transcriptome of the mouse trigeminal ganglion and brainstem: potential mechanisms underlying headache and trigeminal pain presentation in COVID-19
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Supplementary Material 2: Supplementary Fig. 2. Enriched Gene Ontology Terms in Up- and Down-Regulated Genes in TG. Functional enrichment analysis of Gene Ontology (GO) terms was performed using enrichGO to identify biological processes significantly associated with up- (A) and down- (B) regulated genes in TG. Results are visualized as dotplots, with each dot representing an enriched GO term. The x-axis indicates the GeneRatio, calculated as the proportion of input genes annotated to a GO term, while the y-axis lists the enriched GO terms. The top 40 GO terms are displayed for both up- and down-regulated gene sets. Dot size corresponds to the number of genes mapped to each term, and dot color represents the statistical significance of enrichment (adjusted p-value), with red indicating higher significance and blue lower significance.
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