Additional file 2 of Maternal migraine and offspring ADHD: triangulating the evidence
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Additional file 2. Tables S1–S10. Table S1 The baseline characteristics for mothers who completed and did not complete questionnaires collected at 12 weeks’ gestation. Table S2 Associations between polygenic risk scoresand migraine/ADHD traits. Table S2A Association between maternal migraine PRS and offspring ADHD traits. Table S2B Association between ADHD-PRS and migrainein mothers from ALSPAC. Table S3 Harmonized SNP data for two-sample MR to estimate the causal effect of genetic liability to migraine on ADHD. Table S4 Heterogeneity and horizontal pleiotropy test for IVs. Table S5 Estimated causal effect of genetic liability to migraine on ADHD using IVs validated in ALSPAC data during pregnancy. Table S6 Harmonized SNP data for two-sample MR to estimate the causal effect of genetic liability to migraine on ADHD. Table S7 Harmonized SNP data for two-sample MR to estimate the causal effect of genetic liability of migraine on ADHD. Table S8 Secondary sensitivity analysis—MR estimation for causal effect of genetic liability to migraine on ADHD. Table S9 Harmonized SNP data for two-sample MR to estimate the causal effect of genetic liability to ADHD on migraine. Table S10 Heterogeneity and horizontal pleiotropy test for IVs.
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