Maternal BMI, early-life growth, and atopic dermatitis by age 3 years
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Le résumé fourni par la source
Background: Childhood atopic dermatitis is associated with maternal gestational weight gain, whereas an association with prepregnancy body mass index (ppBMI) or fetal and newborn anthropometric measurements is unclear. Objective: Our aim was to determine whether, primarily, maternal ppBMI and, secondarily, offspring newborn anthropometric measurements or fetal growth are associated with atopic dermatitis by age 3 years. Methods: In 2107 mother-child pairs (54% boys) from the general population-based Scandinavian PreventADALL (Preventing Atopic Dermatitis and Allergies) cohort, maternal ppBMI was reported at time of enrollment (at midpregnancy). Thoracic and abdominal circumferences were measured by ultrasound at midpregnancy and again at birth, as were weight and length. Fetal growth, including thoracic and abdominal growth and fetal weight gain, was estimated from midpregnancy to birth. Atopic dermatitis was diagnosed using standard criteria at 3, 6, 12, 24, and age 36 months. Results: Atopic dermatitis was diagnosed in 525 of the 2107 children (25%) by age 3 years, with a positive association with increasing maternal BMI (adjusted odds ratio [aOR] per BMI unit = 1.03 [95% CI = 1.00-1.06]). Furthermore, increasing birth length (mean = 50.5 ± 2.0 cm) was positively associated with atopic dermatitis (aOR = 1.06 [95% CI = 1.01-1.12]), whereas short birth length (<48 cm) was inversely associated with atopic dermatitis (aOR = 0.71 [95% CI = 0.51-1.0]). Neither birth weight nor thoracic, abdominal, or upper arm circumference at birth nor fetal growth was associated with atopic dermatitis. Conclusion: Increasing maternal ppBMI and increasing birth length were positively associated with offspring atopic dermatitis by age 3 years, whereas short birth length was associated with a lower risk of atopic dermatitis.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Maternal BMI, early-life growth, and atopic dermatitis by age 3 years
- Date Crossref
- 01/05/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Bergen Department of Global Public Health and Primary Care pays non établi dans la noticeUniversité ou école supérieure
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Oslo University Hospital Division of Paediatric and Adolescent Medicine pays non établi dans la noticeÉtablissement de santé
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Norwegian Directorate of Health pays non établi dans la noticeÉtablissement de santé
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University of Oslo pays non établi dans la noticeUniversité ou école supérieure
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Norwegian Institute of Public Health Department of Chemical Toxicology pays non établi dans la noticeOrganisme public
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Karolinska University Hospital Astrid Lindgren Children's Hospital pays non établi dans la noticeÉtablissement de santé
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Karolinska Institutet Department of Women's and Children's Health pays non établi dans la noticeUniversité ou école supérieure
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Østfold Hospital Trust pays non établi dans la noticeÉtablissement de santé
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Haukeland University Hospital Department of Occupational Medicine pays non établi dans la noticeÉtablissement de santé
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Faculty of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Department of Specialist Professional Development pays non établi dans la noticeInstitution
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Center for Laboratory Medicine pays non établi dans la noticeStructure de recherche
Department of Global Public Health and Primary Care — University of Bergen, Division of Paediatric and Adolescent Medicine — Oslo University Hospital et Norwegian Directorate of Health, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.