Inside Back Cover: Coumarin‐30 Enables Site‐Resolved Detection of Tubulin Ligands by Microscale Thermophoresis (Angew. Chem. Int. Ed. 12/2026)

Le résumé fourni par la source

In the Research Article (e17086), Igor V. Trushkov, Olga A. Ivanova, Nikita B. Gudimchuk, and co-workers establish coumarin-30 as a new versatile fluorescent probe for tubulin, enabling site-resolved detection of diverse ligands. The cover presents an artistic scene in which coumarin-30 casts light onto a tubulin dimer suspended in a deep-water environment. Four colored ligands appear bound to the protein, while their chemical structures emerge as corals growing on the shadow, each arising from a distinct binding site. Art by M. Andreeva.

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