Sex disparities in the associations between accelerometer-measured movement behaviors and subsequent thromboembolism risk in cancer patients
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Le résumé fourni par la source
BACKGROUND: Cancer patients face a markedly elevated risk of thromboembolism (TE), including both venous thromboembolism (VTE) and arterial thromboembolism (ATE), which contribute substantially to morbidity and mortality in this population. OBJECTIVE: This study examined sex disparities in associations between sleep, sedentary behavior (SB), light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), and TE risk, in cancer patients using data from the UK Biobank. METHODS: A longitudinal cohort analysis of 6,765 cancer patients (2,774 men and 3,991 women) from the accelerometry subsample was conducted using Cox proportional hazards and isotemporal substitution models stratified by sex. RESULTS: The incidence of VTE was 3.0% in men versus 2.2% in women, while ATE incidence was 5.0% versus 2.2%, respectively. Compared with high LPA, medium and low durations were associated with 2.75- and 2.88-fold higher VTE risk only in men. Reallocating 1 h per day from sleep or SB to LPA reduced VTE risk by 24% and 19% in men. Low MVPA was associated with 3.35- and 1.59-fold higher ATE risk in women and men, respectively. Reallocating 1 h per day from sleep, SB, or LPA to MVPA reduced ATE risk by 71%, 70%, and 66%, respectively, only in women. CONCLUSIONS: LPA was associated with a lower risk of VTE only in male cancer patients, whereas MVPA was linked to a lower risk of ATE in female patients, indicating sex-specific associations between movement behaviors and TE risk.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Sex disparities in the associations between accelerometer-measured movement behaviors and subsequent thromboembolism risk in cancer patients
- Date Crossref
- 02/03/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Peking University Clinical Research Institute pays non établi dans la noticeUniversité ou école supérieure
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Capital Medical University Beijing Chao-Yang Hospital pays non établi dans la noticeÉtablissement de santé
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Beijing Chaoyang Emergency Medical Center pays non établi dans la noticeÉtablissement de santé
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Chinese Academy of Medical Sciences & Peking Union Medical College pays non établi dans la noticeUniversité ou école supérieure
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Peking Union Medical College Hospital pays non établi dans la noticeÉtablissement de santé
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Ministry of Education of the People's Republic of China pays non établi dans la noticeOrganisme public
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School of Nursing pays non établi dans la noticeUniversité ou école supérieure
Clinical Research Institute — Peking University, Beijing Chao-Yang Hospital — Capital Medical University et Beijing Chaoyang Emergency Medical Center, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.