A portable, low-cost, point-of-care DNA amplification kit with impedance-based detection for decentralized antimicrobial resistance diagnostics

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copies per μl) in a complex background DNA mixture demonstrated detection results that strongly correlated with quantitative PCR (qPCR). These findings demonstrate that the amplification kit achieves performance parity with gold-standard nucleic acid detection methods while offering portability, affordability, and ease of use. By enabling accurate, rapid, and decentralized diagnostics without reliance on laboratory infrastructure, this combined workflow holds promise for advancing infectious disease monitoring and antimicrobial resistance surveillance, among other applications, at the point of care.