Risk factors for renal scarring in individuals with spinal cord injury: A retrospective study
Rattachement africain : kr, us, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
STUDY DESIGN: Retrospective study. OBJECTIVES: To identify risk factors for renal scarring in individuals with spinal cord injury (SCI). SETTING: University-affiliated rehabilitation hospital in Yangsan, Republic of Korea. METHODS: We conducted a retrospective study involving 89 individuals with SCI. Only individuals with an SCI onset of at least six months prior were included to ensure recovery from initial detrusor atonicity. The participants were divided into two groups based on the presence of renal scars, as determined by 99mTc-dimercaptosuccinic acid scan. Demographic and urological data were collected, including the number of symptomatic urinary tract infections (UTIs) during the study period (2019-2023), bladder emptying methods, laboratory renal function tests, results from voiding cystourethrography, and urodynamic study metrics. We adjusted for suspected risk factors using multiple regression analysis. RESULTS: In individuals with SCI, the frequency of symptomatic UTIs (P < 0.001) and female sex (P = 0.02) were significantly associated with the presence of renal scars compared to those without scars. Following adjustment using multiple logistic regression analysis, the history of symptomatic UTIs emerged as the strongest risk factor for renal scarring, with an odds ratio of 3.9 (95% confidence interval: 1.27-11.97, P = 0.021). Using a model based on that predictor, the analysis revealed a predictive capacity with an AUC of 0.711. CONCLUSION: Our study is the first to identify risk factors for renal scarring by analyzing demographic and urological parameters in individuals with SCI, with symptomatic UTI frequency emerging as the strongest risk factor. Our findings suggest that there may be unique, yet undetermined, pathophysiological mechanisms underlying renal scarring in the SCI population.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Risk factors for renal scarring in individuals with spinal cord injury: A retrospective study
- Date Crossref
- 10/02/2026
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Pusan National University Yangsan Hospital pays non établi dans la noticeÉtablissement de santé
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The State University of New Jersey Rutgers pays non établi dans la noticeUniversité ou école supérieure
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Kessler Institute for Rehabilitation pays non établi dans la noticeÉtablissement de santé
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Rutgers New Jersey Medical School pays non établi dans la noticeUniversité ou école supérieure
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Kessler Foundation pays non établi dans la noticeOrganisation à but non lucratif
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Parkside Hospital pays non établi dans la noticeÉtablissement de santé
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Pusan National University pays non établi dans la noticeUniversité ou école supérieure
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Parkside Rehabilitation Hospital pays non établi dans la noticeÉtablissement de santé
Pusan National University Yangsan Hospital, Rutgers — The State University of New Jersey et Kessler Institute for Rehabilitation, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.