Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention
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Le résumé fourni par la source
BACKGROUND: Post-traumatic stress disorder (PTSD) can have detrimental effects for those afflicted and is associated with increased health care utilization and substantial societal costs. Thus, there is a need for accessible, effective, and cost-efficient preventive interventions for post-traumatic psychological sequelae. Research indicates that trauma-focused cognitive-behavioral therapy (CBT-T) could effectively prevent PTSD when applied as an indicated secondary prevention. CIPE is a scalable, low-threshold, therapist-assisted digital CBT-T, which could be readily implemented in services delivering psychosocial support after traumatic incidents if proven effective and cost-effective. The Early Support after Exposure to Trauma (EASE) study evaluates the effectiveness, cost-effectiveness, and implementation of Condensed Internet-delivered Prolonged Exposure (CIPE), applied as an indicated secondary prevention in the context of Norwegian municipal crisis teams. METHODS/DESIGN: The EASE study is a hybrid Type 1 effectiveness and implementation trial. The effectiveness trial is a parallel two-armed multicenter randomized controlled add-on superiority trial, enrolling individuals who receive support from psychosocial crisis teams within 7 weeks after trauma. Participants are randomized to CIPE + treatment as usual (TAU) or TAU only. The primary outcome is the level of PTSD symptoms 6 weeks after randomization (10-13 weeks post trauma). Secondary outcomes include symptoms of depression and insomnia, quality of life, and CIPE cost-effectiveness. The implementation trial examines policy-level factors influencing CIPE implementation, using the Exploration, Preparation, Implementation, Sustainment framework. DISCUSSION: This study will guide further research, policy shaping, and clinical initiatives for implementing preventive interventions aimed at reducing post-traumatic psychological sequelae by integrating evidence-based interventions into routine psychosocial services. TRIAL REGISTRATION: ClinicalTrials.gov NCT06592677 . Registered on 10.09.2024.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention
- Date Crossref
- 05/02/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Oslo Department of Psychology pays non établi dans la noticeUniversité ou école supérieure
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Norwegian Centre for Violence and Traumatic Stress Studies pays non établi dans la noticeStructure de recherche
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NORCE Research AS pays non établi dans la noticeStructure de recherche
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University of California San Diego ACTRI Dissemination and Implementation Science Center pays non établi dans la noticeUniversité ou école supérieure
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University of California pays non établi dans la noticeUniversité ou école supérieure
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Karolinska Institutet pays non établi dans la noticeUniversité ou école supérieure
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Stockholm Health Care Services pays non établi dans la noticeÉtablissement de santé
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Regional Resource Centre on Violence pays non établi dans la noticeInstitution
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Norwegian Research Centre (NORCE) Department of Health and Social Sciences pays non établi dans la noticeStructure de recherche
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Child and Adolescent Services Research Center pays non établi dans la noticeStructure de recherche
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Jonathan and Karin Fielding School of Public Health Department of Health Policy and Management pays non établi dans la noticeUniversité ou école supérieure
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Department of Clinical Neuroscience pays non établi dans la noticeÉtablissement de santé
Department of Psychology — University of Oslo, Norwegian Centre for Violence and Traumatic Stress Studies et NORCE Research AS, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.