Trends and Challenges of Surgical Site Infections Burden in Croatia: A Nationwide Comparative Analysis of Two Point Prevalence Surveys (2017–2023)
Rattachement africain : hr, in. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Surgical site infections (SSIs) are among the most frequent healthcare-associated infections (HCAIs) worldwide. Changes in the functioning of healthcare systems may affect the implementation of SSIs prevention practices, with consequent alterations in the occurrence of HCAIs. The main aims of our study were to analyze specific SSIs prevalence and proportions together with overall HCAIs prevalence in acute care hospitals (ACHs) before and after the COVID-19 pandemic. Additional aims were to identify bacterial causative agents, the use of perioperative antibiotic prophylaxis (PAP), related structural and process quality indicators, and to determine trends between two periods. Methods: The National Reference Centre for HCAIs (University Hospital Centre Zagreb) conducted point prevalence surveys in May 2017 and May 2023 in ACHs throughout Croatia, using the technical protocol developed by the European Centre for Disease Prevention and Control (ECDC). Results: The prevalence of HCAIs in ACHs in Croatia rose from 5.3% (95% CI 4.8–5.7) in 2017 to 7.2% (95% CI 6.6–7.8) in 2023 (p = 9.93 × 10−14). This trend was paralleled with the rising of the HCAIs prevalence in surgical departments from 5.1% to 6.7% (p = 0.0099). The prevalence of overall SSIs across ACHs increased from 0.9% (95% CI 0.7–1.1) in 2017 to 1.2% (95% CI 1.0–1.5) in 2023 (OR 1.36 (1.03–1.80), p = 0.032. While the prevalence of superficial incisional SSIs significantly decreased (OR 0.53 (0.30–0.95), p = 0.028), the share of deep-seated SSIs (deep incisional and organ/space SSIs) among classified SSIs shifted from 48/92 to 77/96; odds ratio (OR) 2.09 (95% CI 1.45–3.01). In 2017, Gram-positive cocci were the most frequently isolated bacterial causative agents (44.6%). By 2023, this shifted, with Enterobacterales species comprising most isolates (42.2%). In 2023, significantly a higher proportion of patients received PAP (χ2 = 25.419, df = 1, p < 0.5). An increase in the positive trend of alcohol-based hand rub antiseptics use in surgical departments (+15.7 L/patient-days, p < 0.001) contrasted with a decrease in infection prevention and control (IPC) nurses and medical doctors per hospital (−0.5, p = 0.041/−0.5, p = 0.003). Conclusions: Findings of the two point prevalence surveys over time indicate the changes in trends in surgical site infections burden, and highlight the need for the implementation and strengthening of preventive measures with the focus on targeted prevention of deep-seated infections.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Trends and Challenges of Surgical Site Infections Burden in Croatia: A Nationwide Comparative Analysis of Two Point Prevalence Surveys (2017–2023)
- Date Crossref
- 02/02/2026
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Hrvatski zavod za javno zdravstvo pays non établi dans la noticeInstitution
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University Hospital Centre Zagreb Department of Clinical and Molecular Microbiology pays non établi dans la noticeÉtablissement de santé
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University of Zagreb pays non établi dans la noticeUniversité ou école supérieure
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Croatian Chamber of Economy pays non établi dans la noticeInstitution
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Institute of Public Health Bengaluru pays non établi dans la noticeOrganisation à but non lucratif
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Institute for Medical Research and Occupational Health pays non établi dans la noticeStructure de recherche
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Institute of Economics Zagreb pays non établi dans la noticeInstitution
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Sisters of Charity Hospital pays non établi dans la noticeÉtablissement de santé
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Antimicrobial Resistance Prevention Laboratory Diagnostics Unit pays non établi dans la noticeStructure de recherche
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School of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Croatian Medical Chamber pays non établi dans la noticeInstitution
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Public Health Institute Zagreb County Department of Microbiology pays non établi dans la noticeStructure de recherche
Hrvatski zavod za javno zdravstvo, Department of Clinical and Molecular Microbiology — University Hospital Centre Zagreb et University of Zagreb, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.