Systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles
Rattachement africain : dk, de, ch, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background Ultrafine particles (≤100 nm diameter) may have a higher toxicity than larger particles but are still not regulated nor part of routine air pollution monitoring. So far, health effects of long-term exposure to ambient ultrafine particles are not well understood, owing to a lack of exposure data and epidemiological studies. Methods We conducted a systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles, including studies published until December 2024. A meta-analysis was conducted for outcomes with at least four available effect estimates. Confidence in the body of evidence was evaluated using the Office of Health Assessment and Translation method. Results We identified 85 studies investigating various mortality, morbidity and subclinical outcomes. In meta-analyses of single-pollutant models, we found positive associations with natural mortality (hazard ratio 1.06, 95% CI 1.04–1.08) and C-reactive protein (10.14% increase (95% CI −0.51–21.99%) per 10 000 pt·cm −3 increase in long-term exposure to ultrafine particles, with low and inadequate levels of evidence, respectively. The remaining studies revealed overall limited evidence for adverse effects on a wide range of outcomes. Less than half of the studies adjusted for co-pollutants. Conclusion The evidence base on long-term health effects of ultrafine particles has increased substantially in the past decade, while the overall evidence for independent effects of long-term ultrafine particle exposure remains inadequate to low. More studies are needed to draw firm conclusions about the independent adverse effects of long-term ultrafine particles on various health end-points, with a special focus on the influence of co-pollutant adjustment.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles
- Date Crossref
- 01/01/2026
- Éditeur
- European Respiratory Society (ERS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Copenhagen Department of Public Health pays non établi dans la noticeUniversité ou école supérieure
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Heinrich Heine University Düsseldorf pays non établi dans la noticeUniversité ou école supérieure
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Swiss Tropical and Public Health Institute pays non établi dans la noticeStructure de recherche
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University of Basel pays non établi dans la noticeUniversité ou école supérieure
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Health Effects Institute pays non établi dans la noticeOrganisation à but non lucratif
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Hochschule Düsseldorf University of Applied Sciences pays non établi dans la noticeUniversité ou école supérieure
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Medical Faculty Institute of Occupational pays non établi dans la noticeUniversité ou école supérieure
Department of Public Health — University of Copenhagen, Heinrich Heine University Düsseldorf et Swiss Tropical and Public Health Institute, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.