Associations between impaired awareness of hypoglycaemia and mental health in insulin‐treated type 2 and type 1 diabetes in the Hypo‐ METRICS study
Rattachement africain : ie, gb, nl, dk, no. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
AIMS: The mental health impact of impaired awareness of hypoglycaemia (IAH) in people with type 2 diabetes (T2D) is not known. We explored this in people with insulin-treated T2D and type 1 diabetes (T1D). METHODS: Hypo-METRICS was a 10-week cross-sectional observation of hypoglycaemia experience, collecting data on glucose and activity. Participants (325 insulin-treated T2D, 277 T1D) completed questionnaires scoring depression (PHQ-9), anxiety (GAD-7), diabetes distress (PAID) and fear of hypoglycaemia (HFS-II [worry]) at baseline. IAH was defined as a Gold score ≥4. Relationships between IAH and mental health scores were explored using unadjusted and adjusted generalised linear regression analyses. Age, sex, race, diabetes duration, level of education, employment status, continuous glucose monitoring (CGM) use, hypoglycaemia, use of anti-depressants and use of anti-anxiety medications were covariates in the adjusted regression. RESULTS: In unadjusted regression in insulin-treated T2D, IAH was associated with higher PHQ-9 (6.4% [1.5%-11.3%]; p = 0.011), GAD-7 (7.6% [2.1%-13%]; p = 0.006) and HFS-II (worry) (7.4% [2.8%-12%]; p = 0.002) scores, with no differences in PAID (p = 0.655). After adjustment, IAH was associated with higher HFS-II (worry) (5.3% [0.3%-10.6%]; p = 0.048) only. In T1D, IAH was associated with higher PHQ-9 (6.2% [1.3%-10.8%]; p = 0.012), GAD-7 (6.1% [0.1%-12.2%]; p = 0.046) and HFS-II (worry) (6.1% [0.06%-11.5%]; p = 0.029) scores, but not PAID (p = 0.654), all unadjusted. These relationships remained after adjustment, which also showed higher PAID (8.43% [2.62%-14.24%]; p = 0.005). CONCLUSION: Our data demonstrated associations between IAH and a greater mental health burden in both insulin-treated T2D and T1D. Addressing these mental health challenges should be an important part of the holistic care of people with IAH and insulin-treated diabetes.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Associations between impaired awareness of hypoglycaemia and mental health in insulin‐treated type 2 and type 1 diabetes in the Hypo‐ <scp>METRICS</scp> study
- Date Crossref
- 23/01/2026
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
University College Dublin pays non établi dans la noticeUniversité ou école supérieure
-
University of Leicester pays non établi dans la noticeUniversité ou école supérieure
-
National University of Ireland pays non établi dans la noticeUniversité ou école supérieure
-
Radboud University Nijmegen pays non établi dans la noticeUniversité ou école supérieure
-
King's College London pays non établi dans la noticeUniversité ou école supérieure
-
Radboud University Medical Center pays non établi dans la noticeOrganisme public
-
King's College School pays non établi dans la noticeUniversité ou école supérieure
-
Steno Diabetes Centers pays non établi dans la noticeÉtablissement de santé
-
University of Southern Denmark pays non établi dans la noticeUniversité ou école supérieure
-
Western Norway University of Applied Sciences pays non établi dans la noticeUniversité ou école supérieure
-
Odense Municipality pays non établi dans la noticeOrganisme public
-
Danish Diabetes Academy pays non établi dans la noticeStructure de recherche
University College Dublin, University of Leicester et National University of Ireland, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.