Comprehensive Assessment of Direct and Passive Smoking Across the Pancreatitis Spectrum
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Le résumé fourni par la source
OBJECTIVES: Smoking is a key risk factor for pancreatitis, contributing to pathogenesis and disease progression. Data regarding second-hand smoking, or passive smoking (PS) exposure, are lacking. We therefore aimed to assess the impact of PS exposure across the pancreatitis spectrum. METHODS: We analyzed baseline data from the PROCEED study, a multicenter study in the United States including patients with acute (AP), recurrent acute (RAP), and chronic (CP) pancreatitis. Participants detailed their individual smoking history and PS exposure, which was compared between AP, RAP, and CP subgroups. Participant factors and clinical characteristics were compared by level of individual and PS exposure. RESULTS: Among 1369 participants (190 AP, 498 RAP, 681 CP), 346 (25.3%) were current and 409 (29.9%) were former smokers. The CP subgroup had the highest proportion of current smokers (36.7% CP vs 15.1% RAP, 11.1% AP, P < 0.001). PS exposure was also significantly higher in the CP subgroup (68.6% CP vs 58.2% RAP, 55.3% AP, P < 0.001). A minority (16.3%) with CP reported no smoking exposure (by self or passive) while nearly half smoked ≥20 pack-years. The mean PS duration was significantly higher in CP participants (21.8 y) compared with those with AP (17.8 y) or RAP (18.9 y) ( P < 0.0166). CONCLUSIONS: In this multicenter study, we affirmed an association with smoking use and intensity with CP-related complications. For the first time, we report a high prevalence of prior exposure to passive smoking in all pancreatitis subtypes, which requires further study to understand the impact on disease outcomes.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Comprehensive Assessment of Direct and Passive Smoking Across the Pancreatitis Spectrum
- Date Crossref
- 16/01/2026
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Mayo Clinic in Arizona Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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University of Minnesota Department of Pediatrics pays non établi dans la noticeUniversité ou école supérieure
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MNGI Digestive Health pays non établi dans la noticeÉtablissement de santé
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University of Minnesota Medical Center pays non établi dans la noticeÉtablissement de santé
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University of Pittsburgh Medical Center Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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The University of Texas MD Anderson Cancer Center pays non établi dans la noticeÉtablissement de santé
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Baylor College of Medicine Department of Surgery pays non établi dans la noticeUniversité ou école supérieure
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Indiana University – Purdue University Indianapolis Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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University of Florida Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Florida College pays non établi dans la noticeUniversité ou école supérieure
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The Ohio State University Wexner Medical Center Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Cedars-Sinai Medical Center Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
Department of Internal Medicine — Mayo Clinic in Arizona, Department of Pediatrics — University of Minnesota et MNGI Digestive Health, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.