A Systematic and Narrative Review of Safety and Complications in Minimally Invasive Glaucoma Surgery (MIGS) Between 2014–2024
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Le résumé fourni par la source
Introduction: Earlier intervention in glaucoma has been suggested to slow disease progression and preserve visual function and quality of life. Consequently, minimally invasive glaucoma surgery (MIGS) is increasingly used in mild-to-moderate glaucoma. Although numerous techniques and devices are available, their comparative efficacy remains debated: most procedures lower intraocular pressure to the mid-teens in primary open-angle glaucoma, but without clear evidence of superiority. As these surgeries are now offered to younger, otherwise healthy patients, safety has therefore become a central criterion in technique selection. Methods: This PRISMA-based systematic review analyzed safety outcomes from peer-reviewed studies of the main MIGS procedures published between 2014 and 2024. Five databases were searched using current and historical device names. Non-clinical studies, case series, and nonstandard techniques were excluded from quantitative analysis but retained qualitatively to capture rare events. A total of 401 studies, representing 39,381 eyes and 68,917 eye-years of follow-up, were included. Highest reported and weighted mean complication rates were calculated by procedure type. Results: Safety profiles varied. Trabecular bypass implants and ab interno canaloplasty were associated with low rates of serious adverse events and minimal anatomical disruption. Suprachoroidal devices carried higher risks of hypotony, inflammation, and malposition. Across all categories, chronic changes to angle anatomy and occasionnal re-interventions highlighted the potential for long-term sequelae, with endothelial cell loss emerging as a key concern for certain procedures.However, heterogeneity in definitions and reporting limited comparability. Common events such as hyphema and IOP spikes were inconsistently documented, while late complications like endothelial cell loss or peripheral anterior synechiae were often overlooked. This underreporting risks conflicting conclusions and undermines comparisons. Conclusion: For patients with mild, stable disease or those undergoing opportunistic combined surgery, tissue-sparing procedures with the lowest observed complication rates may be preferable. Standardized definitions, long-term follow-up, and harmonized safety reporting are becoming essential.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A Systematic and Narrative Review of Safety and Complications in Minimally Invasive Glaucoma Surgery (MIGS) Between 2014–2024
- Date Crossref
- 01/01/2026
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Geneva pays non établi dans la noticeUniversité ou école supérieure
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Queen Mary University of London pays non établi dans la noticeUniversité ou école supérieure
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London School of Business and Management pays non établi dans la noticeUniversité ou école supérieure
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HES-SO Genève pays non établi dans la noticeUniversité ou école supérieure
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Institut de la Vision INSERM-DGOS CIC 1423 pays non établi dans la noticeStructure de recherche
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Inserm pays non établi dans la noticeOrganisme public
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Université Paris-Saclay pays non établi dans la noticeUniversité ou école supérieure
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Centre hospitalier national d'ophtalmologie des Quinze-Vingts pays non établi dans la noticeÉtablissement de santé
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Sorbonne Université pays non établi dans la noticeUniversité ou école supérieure
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Assistance Publique – Hôpitaux de Paris pays non établi dans la noticeÉtablissement de santé
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Hôpital Ambroise-Paré pays non établi dans la noticeÉtablissement de santé
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University Hospitals Birmingham NHS Foundation Trust Department of Ophthalmology pays non établi dans la noticeÉtablissement de santé
University of Geneva, Queen Mary University of London et London School of Business and Management, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.