[症例報告]A case of spontaneous intestinal perforation following cytotoxic therapy of a primary multiple malignant lymphoma

Le résumé fourni par la source

We report a case of diffuse large B cell lymphomas in the small intestine with perforative peritonitis. A 55-year-old man presented with the chief complaint of spontaneous back pain and was diagnosed as having multiple primary malignant lymphoma of the small intestine with a metastatic vertebral tumor after undergoing a complete medical examination. The patient thereafter underwent chemotherapy accompanied by radiotherapy. After the third week of medication was completed, the patient started complaining of severe abdominal pain. Abdominal computed tomography revealed free air. An emergency laparotomy confirmed a diagnosis of perforative peritonitis. Multiple white nodules were observed in the small intestine approximately 10 cm to 280 cm from the ligament of Treiz. The site of perforation correlated with one of the nodules. Partial resection of the small intestine was performed. Histological examinations revealed an abscess and inflammation of the serous side of the intestine, and no malignant cells. These findings suggested that the thickened wall of the ulcer may have been the result of the chemo-radiotherapy and thus was considered to be the cause of the perforation. We recommend that caution should be taken in case of perforation, because an excellent outcome after surgical intervention depends on an early diagnosis and prompt exploration.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.