[Diabetes mellitus in newborns and infants--differences and similarities based on observation of 2 cases].

Le résumé fourni par la source

BACKGROUND: Diabetes mellitus occurs rarely in the early childhood. Recently, the number of reports about diabetes mellitus has increased in the youngest children. OBJECTIVES: The purpose of this study was to investigate the problems of diabetes mellitus in infants, particularly difficulties in the diagnosis and treatment, based on 2 own cases. MATERIAL AND METHODS: Two case reports are shown with their clinical pictures and laboratory analysis. Diabetes mellitus was diagnosed in the age of 4 months (case 1) and in the age of 5 weeks (case 2). RESULTS: Genetic (DRB1*03; DRB1*04) and immunologic examination (IAA, anti-GAD) were positive in case 1 and negative in case 2. CONCLUSIONS: We concluded different etiology of diabetes mellitus in infants. Report of case 1 shows autoimmune type I diabetes mellitus and report of case 2 suggests diabetes mellitus induced by inefficient pancreas damaged during the pathologic pregnancy.

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