Antiphospholipid antibodies and recurrent abortion.
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
We examined the association between anticardiolipin antibodies, lupus anticoagulant, and the risk of recurrent spontaneous abortion in a case-control study conducted in a network of general and teaching hospitals in northern Italy. Subjects consisted of 220 women with two or more unexplained consecutive spontaneous abortions and 193 controls admitted for acute conditions other than immunologic, infective, gynecologic, or cardiovascular. Lupus anticoagulant was detected in 16 of 220 cases (7%, 95% confidence interval 4-11%) but in none of the 193 controls (Fisher exact test, P less than .001). Increased anticardiolipin antibody levels were demonstrated in 19 of 99 cases (19%, 95% confidence interval 12-31%) (seven immunoglobulin (Ig) G, eight IgM, and four IgG and IgM) and in four (all IgG) of 157 controls (3%) for whom data were available. These results offer quantitative evidence on the association between antiphospholipid antibodies and recurrent abortion.
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Où se fait cette recherche
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Mario Negri Institute for Pharmacological Research pays non établi dans la noticeOrganisation à but non lucratif
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico pays non établi dans la noticeÉtablissement de santé
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Azienda Ospedaliero-Universitaria delle Marche pays non établi dans la noticeÉtablissement de santé
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Istituto di Ricerche Farmacologiche Mario Negri pays non établi dans la noticeInstitution
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Istituto di Ricerche Farmacologiche “Mario Negri” pays non établi dans la noticeInstitution
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Ospedali Riuniti Di Bergamo pays non établi dans la noticeInstitution
Mario Negri Institute for Pharmacological Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico et Azienda Ospedaliero-Universitaria delle Marche, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.