Behavioural changes in exposure patterns after genetic counselling among asymptomatic first-degree relatives of patients with pulmonary fibrosis and carriers of a telomere-related gene variant

Résumé fourni par la source

Extract Exposure to tobacco and profibrotic agents contributes to pulmonary fibrosis in relatives of patients carrying a telomere-related gene (TRG) variant [1]. Relatives may know their genetic status in cascade testing, and most of them don't report regret of having genetic testing whatever the results [2]. We hypothesized that the results of genetic cascade testing induces/triggers behavioral changes regarding environmental exposures. The study aims to describe past and current exposures among relatives of patients carrying a TRG variant and to compare behavior changes between carriers and non-carriers after genetic counselling.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.