The effectiveness of the prevention of dental caries by combinations of oral hygiene products with aminofluoride and nanohydroxyapatite

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The comparative effectiveness of nanohydroxyapatite (nanoHAP) and fluoride oral hygiene products is debatable. Some researchers point to the advantage of nanoHAP; other researchers claim the advantage of fluorides, while others do not identify significant differences between them. Most nanoHAP- studies are in vivo and have been studied for a short time; there are not enough studies investigating the effectiveness of combinations of basic and additional oral hygiene products. These problems were the basis for our research. The aim: to study the effectiveness of dental caries prevention with various combinations of nanoHAP and aminofluoride oral hygiene products. Material and methods: 140 children (7–9 years old) were examined before and after preventive measures. Three groups were formed: group 1 used aminofluoride-toothpaste and nanoHAP-mouthwash (46 children); group 2 used nanoHAP-toothpaste and nanoHAP- mouthwash (46 children), group 3 used aminofluoride-toothpaste (48 children). We used the following indices to evaluate the effectiveness of caries prevention: DMFS-indices, intensity increase of caries (ΔDMF), caries reduction, the enamel acid resistance test and the saliva microcrystallization test. Results and discussion: After a year of preventive measures, the intensity increase of caries in the 1st group was ΔDMF=0.3 (32 % caries reduction); in the second group the intensity increase of caries was ΔDMF=0.52; in the third group the intensity increase of caries was ΔDMF=0.45 (13 % caries reduction). The values of the enamel acid resistance test and the saliva microcrystallization test by the 9th month were significantly higher in the 1st group. Conclusion. Fluorides must necessarily be included in the individual oral hygiene for the prevention of dental caries in children. A combination of oral hygiene products aminofluoride- toothpaste and nanoHAP-mouthwash provides a greater caries reduction and changes the enamel acid resistance test and the saliva microcrystallization test, more effectively than a combination of nanoHAP-toothpaste with and nanoHAP-mouthwash or aminofluoride-toothpaste without mouthwash.

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