Comparative effects of different exercise interventions on the mental health of cancer patients: A systematic review and network meta-analysis

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Background: Exercise is recognized as an effective non-pharmacological interven­tion to improve psychological outcomes in cancer patients, but comparative evidence across exercise types remains unclear. Methods: A systematic review and network meta-analysis of 40 randomized controlled trials involving 4082 cancer patients was conducted to compare exercise modalities on quality of life and fatigue. Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated, and moderation analyses examined interven­tion duration and personalization. Results: High-intensity interval training (HIIT) showed the greatest psychological benefits, producing the largest fatigue reduction (SMD = 0.78, 95% CI: 0.52–1.04). Interventions lasting 16–24 weeks demonstrated optimal overall effects. Higher levels of supervision significantly enhanced outcomes, with personalized programs outper­forming low-personalization approaches. Conclusion: HIIT and personalized, adequately long exercise programs provide the most effective psychological improvements for cancer patients. These findings support the integration of structured and individualized exercise pre­scriptions into routine cancer care.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.